NEW STEP BY STEP MAP FOR BOSENTAN

6 The phosphodiesterase-five inhibitor sildenafil is certified for PAH in FC I–IV within the USA and FC II–III in Europe. Endothelin receptor antagonists (ERAs) such as bosentan, sitaxentan and ambrisentan are oral therapies licensed for use in PAH. As no oral agent has proven superiority there stays discussion regarding which really should be